RECURRING ABORTION
Keywords:
Miscarriage, recurrent pregnancy loss, live births rate, pregnancy, reproductionAbstract
Human beings suffer elevated pregnancy failure rates after conception, reaching 10 to 15% of all clinically recognized pregnancies. The high psychological burden and frustration is common among couples who experience a miscarriage and moreover in those who present with recurrent pregnancy loss. This entity doesn’t have a clear definition, and it is described as the loss of 2 or 3 consecutive pregnancies before 20 weeks of gestation according to the American and European currents, respectively. It presents in 1 to 5% of couples who try to conceive depending on the definition used. Recurrent pregnancy loss majorly results from genetic causes which are greatly influenced by advanced maternal age. However, this is a multifactorial disorder in which not only genetic factors may play a role but anatomic, thrombophilia, endocrinologic, immunologic, infectious, and life style factors as well. Even after an exhaustive evaluation the underlying cause remains undetermined in up to 50% of cases.
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